In 2010,Liu, Yang; Huang, Liping; Xie, Fuchun; Hu, Youhong published 《Base-Promoted One-Pot Tandem Reaction of 3-(1-Alkynyl)chromones under Microwave Irradiation to Functionalized Amino-Substituted Xanthones》.Journal of Organic Chemistry published the findings.Synthetic Route of C8H6BrN The information in the text is summarized as follows:
A base-promoted one-pot tandem reaction has been developed from 3-(1-alkynyl)chromones, e.g., I, with various acetonitriles to afford functionalized amino-substituted xanthones, e.g., II, under microwave irradiation This tandem process involves multiple reactions, such as Michael addition/cyclization/1,2-addition, without a transition metal catalyst. This method provides an efficient approach to build up natural product-like diversified amino-substituted xanthone scaffolds rapidly.2-(3-Bromophenyl)acetonitrile(cas: 31938-07-5Synthetic Route of C8H6BrN) was used in this study.
According to other reports, 2-(3-Bromophenyl)acetonitrile(cas: 31938-07-5) is used in the preparation of diarylpyrimidines (DAPYs) as HIV-1 non-nucleoside reverse transcriptase inhibitors.Synthetic Route of C8H6BrN
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts