Application of 50743-32-3On May 1, 1981 ,《Synthesis of 3-substituted-5-oxo-5H-[1]benzopyrano[2,3-b]pyridine derivatives》 appeared in Heterocycles. The author of the article were Ishiguro, Toshihiro; Ukawa, Kiyoshi; Sugihara, Hirosada; Nohara, Akira. The article conveys some information:
Oxobenzopyranopyridines I (R = H, 7-Me, 7-Et, 7-Me2CH, 7-Me3C, 7-Cl, 7-Me2CHO, 9-MeO, R1 = H; R = 7-Me, R1 = 9-Me; R2 = CN, CHO, alkoxycarbonyl) were prepared by cyclization reactions of the corresponding benzopyrancarboxaldehydes II with acetylenes or active methylene compounds Thus, cyclization of II (R = R1 = H) (III) with HCCCN or HCCCO2Et in DMF gave 32% I (R = R1 = H, R2 = CN) and 49% I (R = R1 = H, R2 = CO2Et), resp. Cyclocondensation of III with CH2[CH(OMe)2]2 in HCO2H containing F3B.OEt2 gave 10% I (R = R1 = H, R2 = CHO). I (R = H; R1 = 7-Et, 7-Me2CH; R2 = CN) were also prepared by hydrogenolysis of the corresponding 2-chloro derivatives of I (R2 = CN). In the part of experimental materials, we found many familiar compounds, such as 6-Isopropyl-4-oxo-4H-chromene-3-carbonitrile(cas: 50743-32-3Application of 50743-32-3)
6-Isopropyl-4-oxo-4H-chromene-3-carbonitrile(cas: 50743-32-3) belongs to nitriles. Nitriles are found in many useful compounds. Nitrile rubber is also widely used as automotive and other seals since it is resistant to fuels and oils. Application of 50743-32-3 Industrially, the main methods for producing nitriles are ammoxidation and hydrocyanation. Both routes are green in the sense that they do not generate stoichiometric amounts of salts.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts