《Cooperative Molybdenum-Thiolate Reactivity for Transfer Hydrogenation of Nitriles》 was written by Hou, Shu-Fen; Chen, Jia-Yi; Xue, Minghui; Jia, Mengjing; Zhai, Xiaofang; Liao, Rong-Zhen; Tung, Chen-Ho; Wang, Wenguang. Synthetic Route of C7H4FN And the article was included in ACS Catalysis in 2020. The article conveys some information:
A half-sandwich molybdenum(II) thiolate complex with a η2-MeCN ligand, Cp*Mo(1,2-Ph2PC6H4S)(η2-NCMe), was found to catalyze transfer hydrogenation of nitriles efficiently with ammonia borane (H3N•BH3) at room temperature, producing primary amines. Through molybdenum-thiolate cooperation, the B-H bond of BH3 is cleaved, affording a Mo(II)-H hydride (Cp*Mo(1,2-Ph2PC6H4S)H(BH2)) with the BH2 moiety captured at the S-Mo unit. In the presence of NH3, Cp*Mo(1,2-Ph2PC6H4S)H(BH2) smoothly achieves the catalytic transfer hydrogenation of nitriles. The results came from multiple reactions, including the reaction of 4-Fluorobenzonitrile(cas: 1194-02-1Synthetic Route of C7H4FN)
4-Fluorobenzonitrile(cas: 1194-02-1) is used as chemical intermediate, solvent for perfumes and pharmaceuticals, stabilizer for chlorinated solvents, HPLC analysis, catalyst and component of transition-metal complex catalysts.Synthetic Route of C7H4FN
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts