In 2016,Hayashi, Shun; Yamazoe, Seiji; Koyasu, Kiichirou; Tsukuda, Tatsuya published 《Application of group V polyoxometalate as an efficient base catalyst: a case study of decaniobate clusters》.RSC Advances published the findings.Electric Literature of C8H6BrN The information in the text is summarized as follows:
The base catalytic activity of the decaniobate cluster (TMA)6[Nb10O28]·6H2O (TMA+ = tetramethylammonium cation) was studied theor. and exptl. D. functional theory calculations showed that the oxygen atoms in the cluster are highly neg. charged and suggested the possibility that the cluster can act as a base catalyst. We demonstrated for the first time that [Nb10O28]6- actually exhibits base catalytic activity for aldol-type condensation reactions including Knoevenagel and Claisen-Schmidt condensation reactions. The catalytic reactions proceeded under ambient conditions, suggesting that [Nb10O28]6- holds promise as a practical strong base catalyst.2-(3-Bromophenyl)acetonitrile(cas: 31938-07-5Electric Literature of C8H6BrN) was used in this study.
2-(3-Bromophenyl)acetonitrile(cas: 31938-07-5) has been used in the synthesis of 2-(1-cyano-1-(3-bromophenyl))methylidene-3-phenylthiazolidine-4,5-dione or a series of aminoethylbiphenyls, novel 5-HT7 receptor ligands.Electric Literature of C8H6BrN
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts