Das, Saikat; Murugesan, Kathiravan; Villegas Rodriguez, Gonzalo J.; Kaur, Jaspreet; Barham, Joshua P.; Savateev, Aleksandr; Antonietti, Markus; Koenig, Burkhard published their research in ACS Catalysis in 2021. The article was titled 《Photocatalytic (Het)arylation of C(sp3)-H Bonds with Carbon Nitride》.Reference of 2-Bromobenzonitrile The article contains the following contents:
Mesoporous graphitic carbon nitride(mpg-CN)as a heterogeneous organic semiconductor photocatalyst for direct arylation of sp3 C-H bonds in combination with nickel catalysis are reported. This protocol has a broad synthetic scope (>70 examples including late-stage functionalization of drugs and agrochems.), was operationally simple, and shows high chemo- and regioselectivities. Facile separation and recycling of the mpg-CN catalyst in combination with its low preparation cost, innate photochem. stability, and low toxicity are beneficial features overcoming typical shortcomings of homogeneous photocatalysis. Detailed mechanistic investigations and kinetic studies indicate that an unprecedented energy-transfer process (EnT) from the organic semiconductor to the nickel complex was operated. In the part of experimental materials, we found many familiar compounds, such as 2-Bromobenzonitrile(cas: 2042-37-7Reference of 2-Bromobenzonitrile)
2-Bromobenzonitrile(cas: 2042-37-7) is a precursor to the quinazolinones, a class of drugs used to treat autoimmune diseases and coronary heart disease. In addition, 2-bromobenzonitrile can be used for the Suzuki coupling reaction.Reference of 2-Bromobenzonitrile
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts