Formula: C7H4BrNIn 2019 ,《Semiheterogeneous Dual Nickel/Photocatalytic (Thio)etherification Using Carbon Nitrides》 was published in Organic Letters. The article was written by Cavedon, Cristian; Madani, Amiera; Seeberger, Peter H.; Pieber, Bartholomaeus. The article contains the following contents:
A carbon nitride material can be combined with homogeneous nickel catalysts for light-mediated cross-couplings of aryl bromides with alcs. under mild conditions. The metal-free heterogeneous semiconductor is fully recyclable and couples a broad range of electron-poor aryl bromides with primary and secondary alcs. as well as water. The application for intramol. reactions and the synthesis of active pharmaceutical ingredients was demonstrated. The catalytic protocol is applicable for the coupling of aryl iodides with thiols as well. In addition to this study using 4-Bromobenzonitrile, there are many other studies that have used 4-Bromobenzonitrile(cas: 623-00-7Formula: C7H4BrN) was used in this study.
4-Bromobenzonitrile(cas: 623-00-7) has been used in the synthesis of 4-iodobenzonitrile via photo-induced aromatic Finkelstein iodination reaction.Formula: C7H4BrN It can also be used as an aryl halide test compound in developing greener reaction conditions for Suzuki cross-coupling between aryl halides and phenyl boronic acid.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts