Zhang, Wei; Tao, Shanqing; Ge, Huaibin; Li, Qiao; Ai, Zhenkang; Li, Xiaoxian; Zhang, Beibei; Sun, Fengxia; Xu, Xiaqing; Du, Yunfei published the artcile< Construction of 2-Arylbenzo[4,5]thieno[2,3-d]thiazole Skeleton via CuCl/S-Mediated Three-Component Reaction>, Quality Control of 886761-96-2, the main research area is arylbenzothienothiazole derivative preparation; bromophenylacetonitrile arylaldehyde sulfur three component reaction copper chloride.
An exclusive thiophene-fused polycyclic π-conjugated 2-arylbenzo[4,5]thieno[2,3-d]thiazole skeleton was constructed via a one-pot CuCl-mediated three-component reaction, using 2-(2-bromophenyl)acetonitrile and aromatic aldehydes as substrates and elemental sulfur as sulfur source in the presence of K2CO3 and 1,10-phenanthroline in DMSO. A plausible reaction mechanism was proposed, which involved formation of benzo[b]thiophen-2-amines through cyclization of 2-bromophenyl acetonitrile and sulfur, and subsequent intramol. condensation/dehydrogenation with aromatic aldehydes.
Organic Letters published new progress about Aryl aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 886761-96-2 belongs to class nitriles-buliding-blocks, and the molecular formula is C8H5BrFN, Quality Control of 886761-96-2.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts