Porter, Thomas C.; Smalley, Robert K.; Teguiche, Mabrouk; Purwono, Bambang published the artcile< Tetrazolo[1,5-a]quinolines and 1,2,3-triazolo[1,5-a]quinazolines by the action of cyano carbanions on 2-azidoaryl carbonyl compounds>, Quality Control of 658-99-1, the main research area is tetrazoloquinoline preparation; quinoline tetrazolo preparation; triazoloquinazoline preparation; quinazoline triazolo preparation; cyano carbanion azidophenyl carbonyl compound cyclocondensation.
In protic solvents, 2-N3C6H4CHO undergoes base-catalyzed condensation with cyano carbanions to yield tetrazolo[1,5-a]quinolines, whereas in aprotic media 1,2,3-triazolo[1,5-a]quinazolines are formed. Triazoloquinazolines are also obtained from 2-N3C6H4Ac and from 2-N3C6H4CN, whereas with 2-N3C6H4COCl hydroxytetrazoloquinolines result. 2,1-Oxazolo[4,3-c]tetrazolo[1,5-a]quinolines are obtained by the action of selected cyano carbanions on 2-N3C6H4CN+O- and a 1,2,3-triazolo[1,5-a]quinoline by base-catalyzed condensation of 2-N3C6H4CN with (PhCH2)2CO.
Synthesis published new progress about Aromatic carbonyl compounds Role: RCT (Reactant), RACT (Reactant or Reagent). 658-99-1 belongs to class nitriles-buliding-blocks, and the molecular formula is C8H5F2N, Quality Control of 658-99-1.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts