《Cobalt-catalyzed acylation-reactions of (hetero)arylzinc pivalates with thiopyridyl ester derivatives》 was written by Lutter, Ferdinand H.; Grokenberger, Lucie; Hofmayer, Maximilian S.; Knochel, Paul. Product Details of 105942-08-3This research focused onthiopyridyl ester hetero arylzinc pivalate acylation catalyst; aryl ketone preparation. The article conveys some information:
A cobalt-catalyzed acylation reaction of various primary, secondary and tertiary alkyl, benzyl and (hetero)aryl S-pyridyl thioesters with (hetero)arylzinc pivalates was reported. The thioesters were prepared directly from the corresponding carboxylic acids under mild conditions, thus tolerating sensitive functional groups. Acylations of α-chiral S-pyridyl esters proceeded with very high stereoretention leaded to optically enriched α-chiral ketones.4-Bromo-2-fluorobenzonitrile(cas: 105942-08-3Product Details of 105942-08-3) was used in this study.
4-Bromo-2-fluorobenzonitrile(cas:105942-08-3) is used as a OLED intermediate, Pharmaceutical, electronic and chemical intermediate.Product Details of 105942-08-3 It is used in the synthesis of heterocycles and liquid crystals.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts