Liu, Jian’s team published research in Tetrahedron Letters in 2006-07-17 | 658-99-1

Tetrahedron Letters published new progress about Nitriles Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 658-99-1 belongs to class nitriles-buliding-blocks, and the molecular formula is C8H5F2N, Quality Control of 658-99-1.

Liu, Jian; Jian, Tianying; Sebhat, Iyassu; Nargund, Ravi published the artcile< Preparation of 2,3-dihydro-1H-spiro[isoquinoline-4,4'-piperidine] via an N-sulfonyl Pictet-Spengler reaction>, Quality Control of 658-99-1, the main research area is spiro isoquinoline piperidine dihydro preparation sulfonyl Pictet Spengler reaction.

A high yielding synthesis of variously substituted 2,3-dihydro-1H-spiro[isoquinoline-4,4′-piperidine] is reported. N-(2-nitrophenyl)sulfonyl was successfully used as both an activating and protecting group for the key Pictet-Spengler reaction.

Tetrahedron Letters published new progress about Nitriles Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 658-99-1 belongs to class nitriles-buliding-blocks, and the molecular formula is C8H5F2N, Quality Control of 658-99-1.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts