Hofmann, Fabian’s team published research in Synthesis in 2022-02-28 | 38487-85-3

Synthesis published new progress about Aza-Diels-Alder reaction (stereoselective). 38487-85-3 belongs to class nitriles-buliding-blocks, and the molecular formula is C8H8N2O, Name: 2-Amino-4-methoxybenzonitrile.

Hofmann, Fabian; Gaertner, Cornelius; Kretzschmar, Martin; Schneider, Christoph published the artcile< Asymmetric Synthesis of Fused Tetrahydroquinolines via Intramolecular Aza-Diels-Alder Reaction of ortho-Quinone Methide Imines>, Name: 2-Amino-4-methoxybenzonitrile, the main research area is fused tetrahydroquinoline diastereoselective enantioselective; quinone methide aza Diels Alder chiral Bronsted acid catalyst.

In this concept, the chem. of chiral Bronsted acid bound ortho-quinone methide imines e.g., I was combined to generate a range of interesting fused tetrahydroquinolines e.g., II in a diastereo- and enantioselective manner.

Synthesis published new progress about Aza-Diels-Alder reaction (stereoselective). 38487-85-3 belongs to class nitriles-buliding-blocks, and the molecular formula is C8H8N2O, Name: 2-Amino-4-methoxybenzonitrile.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts