Glover, Christian; Merritt, Eleanor A.; Bagley, Mark C. published the artcile< Synthesis of saramycetic acid>, Electric Literature of 6136-93-2, the main research area is saramycetic acid preparation degradation product thiopeptide antibiotic cyclothiazomycin.
The first reported synthesis of saramycetic acid [2′-acetyl-[2,4′-bithiazole]-4-carboxylic acid], a degradation product of the complex thiopeptide antibiotic cyclothiazomycin, is achieved in nine steps and 11% overall yield from diethoxyacetonitrile by a strategy which incorporates two Hantzsch thiazole syntheses using thioamides prepared from the corresponding nitriles without the use of gaseous H2S. The synthetic material was transformed to Me saramycetate, which had spectroscopic properties in excellent agreement with the literature data.
Tetrahedron Letters published new progress about 6136-93-2. 6136-93-2 belongs to class nitriles-buliding-blocks, and the molecular formula is C6H11NO2, Electric Literature of 6136-93-2.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts