Safety of 4-Cyano-3-fluorophenyl 4-butylbenzoateOn June 3, 2015, Rozwadowski, Tomasz; Massalska-Arodz, Maria; Kolek, Lukasz; Grzybowska, Katarzyna; Bak, Andrzej; Chledowska, Krystyna published an article in Crystal Growth & Design. The article was 《Kinetics of Cold Crystallization of 4-Cyano-3-fluorophenyl 4-Butylbenzoate (4CFPB) Glass Forming Liquid Crystal. I. Nonisothermal Process As Studied by Microscopic, Calorimetric, and Dielectric Methods》. The article mentions the following:
For 4-cyano-3-fluorophenyl 4-butylbenzoate (4CFPB), the process of the crystallization of the CrII phase was studied in microscopic (POM), calorimetric (DSC), and dielec. (BDS) nonisothermal experiments with various (0.5-50 K/min) heating of the metastable nematic phase obtained from its glass. Growth of areas of crystal CrII in the microscopic texture of nematic phase during heating allows estimation of degree of crystallinity D(T) vs temperature curves similar to these obtained basing on DSC heat flow curves and for slow heating with help of dielec. relaxation (BDS) method. Two types of CrII crystallization mechanisms seem to be identified: (1) strong ϕ dependence on temperature of full crystallization Tc(ϕ) and half time of crystallization t1/2(ϕ) on slow heating up to 5 K/min points to diffusion-controlled mechanism with the energy barrier 57 kJ/mol, and (2) small effect of faster heating on Tc(ϕ) and t1/2(ϕ) seems to illustrate thermodn. mechanism with energy barrier 180 kJ/mol. The scenario of two mechanisms of CrII crystallization is in agreement with the results of new method proposed by Mo et al., using combination of Avrami and Ozawa equations for description of nonisothermal crystallization In addition to crystallization of CrII of 4CFPB, at higher temperature range CrII-CrI transformation to a stable CrI crystal was digitalized based on microscopic and DCS results for heating at 1 K/min. In the part of experimental materials, we found many familiar compounds, such as 4-Cyano-3-fluorophenyl 4-butylbenzoate(cas: 86776-52-5Safety of 4-Cyano-3-fluorophenyl 4-butylbenzoate)
4-Cyano-3-fluorophenyl 4-butylbenzoate(cas: 86776-52-5) is a member of aromaticfluorinated building blocks. Depending on which substituents are present, fluoroaromatic intermediates can be converted into fluorinated or fluorine-free commercial end products.Fluorine-containing aromatics have been incorporated into drugs (hypnotics, tranquilizers, antiinflammatory agents, analgesics, antibacterials).Safety of 4-Cyano-3-fluorophenyl 4-butylbenzoate
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts