Formula: C10H7BrN2On November 5, 2014 ,《Influences of halogen atoms on indole-3-acetonitrile (IAN): Crystal structure and Hirshfeld surfaces analysis》 appeared in Journal of Molecular Structure. The author of the article were Luo, Yang-Hui; Yang, Li-Jing; Han, Guangjun; Liu, Qing-Ling; Wang, Wei; Ling, Yang; Sun, Bai-Wang. The article conveys some information:
Crystal structural investigations and Hirshfeld surface anal. of three halogen atoms (4-Cl, 6-Cl and 4-Br) substituted indole-3-acetonitrile (IAN) were reported in this work. The structures of the present three compounds were characterized by IR spectra, Elemental analyses, NMR spectra, differential scanning calorimetry (DSC), thermogravimetric analyses (TGA) and hot stage microscopy (HSM). The Hirshfeld surfaces anal. in terms of crystal structure, intermol. interactions and π···π stacking motifs were performed. The authors found that the different kinds of halogen atoms and the different substituted positions have a significant effect on the crystal structures, mol. π···π stacking motifs, m.ps., and the nature of intermol. interactions for IANs.2-(4-Bromo-3-indolyl)acetonitrile(cas: 89245-35-2Formula: C10H7BrN2) was used in this study.
2-(4-Bromo-3-indolyl)acetonitrile(cas: 89245-35-2) is a member of nitriles. Nitriles have been reduced to amines by many methods, especially by catalytic hydrogenation and by metal hydrides. Aliphatic and aromatic nitriles have also been reduced to nitro derivatives using hydrazinium monoformate in the presence of Raney-nickel.Formula: C10H7BrN2
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts