Computed Properties of C10H7BrN2On September 25, 1985 ,《The chemistry of indoles. XXIV. Syntheses of 3-indoleacetic acid and 3-indoleacetonitrile having a halo group and a carbon functional group at the 4-position》 was published in Chemical & Pharmaceutical Bulletin. The article was written by Somei, Masanori; Kizu, Kiyomi; Kunimoto, Masako; Yamada, Fumio. The article contains the following contents:
Various 4-halo-3-indoleacetic acids and -3-indoleacetonitriles were synthesized for the first time by means of the Sandmeyer or Schiemann reaction, demonstrating the versatility of 4-indolediazonium salts in 4-substituted indole chem. A practical synthetic method for 4-haloindoles consists of regioselective thallation-halogenation, and the products were also converted to 4-halo-3-indoleacetic acids. The first synthesis of 4-formyl-3-indoleacetonitrile is also reported. The results came from multiple reactions, including the reaction of 2-(4-Bromo-3-indolyl)acetonitrile(cas: 89245-35-2Computed Properties of C10H7BrN2)
2-(4-Bromo-3-indolyl)acetonitrile(cas: 89245-35-2) is a member of nitriles. Nitriles have been reduced to amines by many methods, especially by catalytic hydrogenation and by metal hydrides. Aliphatic and aromatic nitriles have also been reduced to nitro derivatives using hydrazinium monoformate in the presence of Raney-nickel.Computed Properties of C10H7BrN2
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts