In 1980,Journal of Organic Chemistry included an article by Schuster, Ingeborg I.; Roberts, John D.. Category: nitriles-buliding-blocks. The article was titled 《Proximity effects on nitrogen-15 chemical shifts of 8-substituted 1-nitronaphthalenes and 1-naphthylamines》. The information in the text is summarized as follows:
The 15N chem. shifts of several title naphthalenes were determined and, except for high-field shifts observed for 8-cyano- or 8-nitro-1-naphthylamine (I), the substituent effects are unexpectedly small. The high-field shifts of the amine nitrogens of I may indicate complexing between the amino group of the proximate substituents of the type suggested by J. D. Dunitz, (1978). The smallness of the other substituent effects may be the result of mutual cancellation of opposing larger effects. The experimental part of the paper was very detailed, including the reaction process of 5-Amino-1-naphthonitrile(cas: 72016-73-0Category: nitriles-buliding-blocks)
5-Amino-1-naphthonitrile(cas: 72016-73-0) belongs to anime. Large quantities of aliphatic amines are made synthetically. The most widely used industrial method is the reaction of alcohols with ammonia at a high temperature, catalyzed by metals or metal oxide catalysts (e.g., nickel or copper). Mixtures of primary, secondary, and tertiary amines are thereby produced.Category: nitriles-buliding-blocks
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts