Recommanded Product: 50743-32-3On March 25, 1986, Kubo, Keiji; Ukawa, Kiyoshi; Kuzuna, Seiji; Nohara, Akira published an article in Chemical & Pharmaceutical Bulletin. The article was 《Synthesis of (3-carboxy-5-oxo-5H-[1]benzopyrano[2,3-b]pyridin-2-yl)acetic acid derivatives, potential antiarthritic agents》. The article mentions the following:
The title compounds I (R = 7-Et, 7-Cl, etc.; R1 = Me, Et, Na) possessed potent antiarthritic activity in the rat adjuvant arthritic model. The mode of action of these compounds differs from that of acidic antiinflammatory drugs. Various modifications in these compounds (e.g., elongation, removal, or substitution of the methylene group of the acetic acid moiety, substitution of the benzene ring) were made in order to study the structure-activity relationships. The structural requirements for the compounds to show activity are rather severe. In the experiment, the researchers used 6-Isopropyl-4-oxo-4H-chromene-3-carbonitrile(cas: 50743-32-3Recommanded Product: 50743-32-3)
6-Isopropyl-4-oxo-4H-chromene-3-carbonitrile(cas: 50743-32-3) belongs to nitriles. Nitriles are found in many useful compounds. Nitrile rubber is also widely used as automotive and other seals since it is resistant to fuels and oils. Organic compounds containing multiple nitrile groups are known as cyanocarbons.Recommanded Product: 50743-32-3
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts