Application of 72016-73-0On November 30, 1979 ,《Chlorine as an activating group in an electrophilic substitution. The Friedel-Crafts acetylation of 1-chloronaphthalene》 appeared in Journal of the Chemical Society. The author of the article were Gore, Peter H.; Khan, Iqtidar M.. The article conveys some information:
The activating effect of chlorine in the Friedel-Crafts acetylation of 1-chloronaphthalene is reported. Compared to naphthalene, the chloro-substituent activated the 4-position by a factor of 5.1 in CHCl3, all other positions being deactivated. In nitromethane, the 2-, 4-, 6- and 7-positions are activated by factors of 4.5, 13, 1.5, and 1.5, resp., all other positions being deactivated. The experimental process involved the reaction of 5-Amino-1-naphthonitrile(cas: 72016-73-0Application of 72016-73-0)
5-Amino-1-naphthonitrile(cas: 72016-73-0) belongs to anime. Amines have a free lone pair with which they can coordinate to metal centers. Amine–metal bonds are weaker because amines are incapable of backbonding, but they are still important for sensing applications.While stronger than hydrogen bonds, amine–metal bonds are still weaker than both covalent and ionic bonds.Application of 72016-73-0
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts