Related Products of 623-00-7In 2020 ,《Supercritical carbon dioxide extraction of a biaryl from model product solutions of a flow Suzuki-Miyaura coupling reaction》 was published in Journal of Chemical Engineering of Japan. The article was written by Fujii, Tatsuya; Kawasaki, Shin-ichiro. The article contains the following contents:
The present study investigates the extraction of a target chem., 4-cyanobiphenyl, from model product solutions of a flow Suzuki-Miyaura coupling reaction. Fast flow extraction from an ethanol aqueous solution of 4-cyanobiphenyl was conducted using supercritical carbon dioxide as the extraction solvent under conditions of 40-60°C and 10-20 MPa. More than 80% of the 4-cyanobiphenyl was recovered in the CO2-rich phase, and the rate was greater than 5.0 g-4-cyanobiphenyl/h for the extraction at 60°C and 20 MPa from the model solution containing salts. The effects of the ethanol mole fraction and the extraction pressure were also investigated to elucidate the effect of changes in the solvent properties on the partitioning behavior. The 4-cyanobiphenyl partition coefficient decreased with increasing ethanol mole fraction and increased with increasing extraction pressure. A model that includes the effects of changes in solubility with increasing CO2 d. and ethanol mole fraction in the water- and CO2-rich phases was developed. The model well represents the tendency of the partitioning behavior, which indicates that the CO2 d. and ethanol mole fraction in each phase are important factors governing the partitioning behavior. In addition to this study using 4-Bromobenzonitrile, there are many other studies that have used 4-Bromobenzonitrile(cas: 623-00-7Related Products of 623-00-7) was used in this study.
4-Bromobenzonitrile(cas: 623-00-7) has been used in the synthesis of 4-iodobenzonitrile via photo-induced aromatic Finkelstein iodination reaction.Related Products of 623-00-7 It can also be used as an aryl halide test compound in developing greener reaction conditions for Suzuki cross-coupling between aryl halides and phenyl boronic acid.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts