Ali, Abdelselam; Bliese, Marianne; Rasmussen, Jo-Anne M.; Sargent, Roger M.; Saubern, Simon; Sawutz, David G.; Wilkie, John S.; Winkler, David A.; Winzenberg, Kevin N.; Woodgate, Ruth C. J. published an article on February 15 ,2007. The article was titled 《Discovery of (Z)-2-phenyl-3-(1H-pyrrol-2-yl)acrylonitrile derivatives active against Haemonchus contortus and Ctenocephalides felis (cat flea)》, and you may find the article in Bioorganic & Medicinal Chemistry Letters.Application In Synthesis of 3-Chloro-4-fluorophenylacetonitrile The information in the text is summarized as follows:
A series of 2-phenyl-3-(1H-pyrrol-2-yl)acrylonitrile derivatives, e.g., I, were synthesized and evaluated for in vitro activity against the endoparasite Haemonchus contortus and the ectoparasite Ctenocephalides felis. Some compounds had significant in vitro activity against these parasites. The experimental process involved the reaction of 3-Chloro-4-fluorophenylacetonitrile(cas: 658-98-0Application In Synthesis of 3-Chloro-4-fluorophenylacetonitrile)
3-Chloro-4-fluorophenylacetonitrile(cas: 658-98-0) belongs to nitriles. Nitriles are found in many useful compounds. Nitrile rubber is also widely used as automotive and other seals since it is resistant to fuels and oils. Organic compounds containing multiple nitrile groups are known as cyanocarbons.Application In Synthesis of 3-Chloro-4-fluorophenylacetonitrile
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts