Chastrette, Maurice’s team published research in Synthesis in 1980-11-30 | 6136-93-2

Synthesis published new progress about Organometallic compounds Role: RCT (Reactant), RACT (Reactant or Reagent). 6136-93-2 belongs to class nitriles-buliding-blocks, and the molecular formula is C6H11NO2, COA of Formula: C6H11NO2.

Chastrette, Maurice; Axiotis, Georges P. published the artcile< An efficient general synthesis of α-amino acetals>, COA of Formula: C6H11NO2, the main research area is nitrile dialkoxy organometallic addition reaction; amino acetal.

Title compounds H2NCRR1CR2(OEt)2 (R = Bu, Ph; R1 = Bu, Ph, H; R2 = H, Ph) were prepared in 60-95% yield by treating (EtO)2CR2CN with RMgBr or BuLi for 12 h at room temperature, adding BuLi, PhLi or LiAlH4 under N for 12-15 h at room temperature, and hydrolyzing the mixture using NH4Cl.

Synthesis published new progress about Organometallic compounds Role: RCT (Reactant), RACT (Reactant or Reagent). 6136-93-2 belongs to class nitriles-buliding-blocks, and the molecular formula is C6H11NO2, COA of Formula: C6H11NO2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts