The author of 《Synthesis of 1,3,4-oxadiazole and imidazo[1,2-a]pyridine based molecular hybrids and their in vitro antituberculosis and cytotoxicity studies》 were Maurya, Shiv Shyam; Gosain, Tannu Priya; Kidwai, Saqib; Singh, Ramandeep; Rawat, Diwan S.. And the article was published in Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry in 2019. Recommanded Product: 4-Cyanobenzyl bromide The author mentioned the following in the article:
A library of novel 1,3,4-oxadiazole substituted imidazo[1,2-a]pyridine based mol. hybrids I (R = Br, Cl, Me; R1 = 2-nitrobenzyl, naphthalen-1-ylmethyl, (E)-geranyl, etc.) have been synthesized and evaluated against mycobacterium tuberculosis H37Rv. Out of 59 compounds synthesized, ten compounds show activity in the range of 3.125-12.5 μM. Compound I (R = Br, R1 = hexyl) is found to be most active with MIC99 value of 3.125-6.25 μM. Further, these ten compounds have also been tested for their toxicity against THP-1 cell line and are found to be non-toxic with TC50 value in the range of (10 – >50 μM) concentration The results came from multiple reactions, including the reaction of 4-Cyanobenzyl bromide(cas: 17201-43-3Recommanded Product: 4-Cyanobenzyl bromide)
4-Cyanobenzyl bromide(cas: 17201-43-3) is a white solid. Its melting point is 113-117°C, and flash point is 125.1°C. It is insoluble in water at 20°C. It is stable under normal temperatures and pressures. It should be stored at 0-5°C.Recommanded Product: 4-Cyanobenzyl bromide
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts