Hou, Chuanwei; He, Qian; Yang, Chunhao published the artcile< Direct Synthesis of Diverse 2-Aminobenzo[b]thiophenes via Palladium-Catalyzed Carbon-Sulfur Bond Formation Using Na2S2O3 as the Sulfur Source>, SDS of cas: 886761-96-2, the main research area is diverse aminobenzothiophene synthesis palladium catalyzed carbon sulfur bond formation; sodium thiosulfate sulfur source aminobenzothiophene synthesis.
A novel and direct synthesis of various 2-aminobenzo[b]thiophenes has been developed. The reactions were catalyzed by a combination of Pd(dppf)Cl2 and dppf using odorless and cheap Na2S2O3 as the sulfur source. This strategy allowed us to synthesize important 2-aminobenzo[b]thiophene scaffold more efficiently and conveniently. Thus, e.g., sulfuration of (2-bromophenyl)acetonitrile with Na2S2O3 in presence of Pd(dppf)Cl2 and dppf afforded 2-aminobenzothiophene in up to 64% yield.
Organic Letters published new progress about Acetylation (nucleophilic substitution of dimethylamine formed in situ from DMF under attempted acetylation conditions). 886761-96-2 belongs to class nitriles-buliding-blocks, and the molecular formula is C8H5BrFN, SDS of cas: 886761-96-2.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts