《Enantioselective H-bond-directing approach for trienamine-mediated reactions in asymmetric synthesis》 was published in Angewandte Chemie, International Edition in 2012. These research results belong to Albrecht, Lukasz; Cruz Acosta, Fabio; Fraile, Alberto; Albrecht, Anna; Christensen, Jannie; Jorgensen, Karl Anker. HPLC of Formula: 50743-32-3 The article mentions the following:
The first H-bond-directed trienamine-mediated [4+2] cycloaddition was developed, thereby demonstrating the viability of such an activation strategy. The reaction between diversely substituted 2,4-dienals and 3-cyanochromones proceeded smoothly and in a highly stereoselective manner in the presence of a squaramide-containing aminocatalyst. Furthermore, it was demonstrated that the obtained cycloadducts can be chemo- and diastereoselectively transformed into polycyclic products with high mol. and stereochem. complexity that possess up to five stereogenic centers. An unexpected stereochem. outcome of the reaction was observed and a rationalization of the results was provided. In the experimental materials used by the author, we found 6-Isopropyl-4-oxo-4H-chromene-3-carbonitrile(cas: 50743-32-3HPLC of Formula: 50743-32-3)
6-Isopropyl-4-oxo-4H-chromene-3-carbonitrile(cas: 50743-32-3) belongs to nitriles. Nitriles are found in many useful compounds. Nitrile rubber is also widely used as automotive and other seals since it is resistant to fuels and oils. Organic compounds containing multiple nitrile groups are known as cyanocarbons.HPLC of Formula: 50743-32-3
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts