In 2022,Zhu, Da-Liang; Jiang, Shan; Young, David James; Wu, Qi; Li, Hai-Yan; Li, Hong-Xi published an article in Chemical Communications (Cambridge, United Kingdom). The title of the article was 《Visible-light-driven C(sp2)-H arylation of phenols with arylbromides enabled by electron donor-acceptor excitation》.Related Products of 2042-37-7 The author mentioned the following in the article:
A catalyst-free visible-light-driven C(sp2)-H arylation of unprotected phenols ROH (R = Ph, naphthalen-2-yl, 3,5-dibromophenyl, etc.) with arylbromides R1Br (R1 = 4-cyclopropanecarbonylbenzen-1-yl, 2-cyanobenzen-1-yl, 3-cyano-5-(trifluoromethyl)phenyl, etc.) to give 2-arylated phenols RR1 have been developed. This reaction proceeds through the excitation of an electron donor-acceptor complex between a phenolate and arylbromide, electron transfer, and debrominative C(sp2)-C(sp2) coupling. The results came from multiple reactions, including the reaction of 2-Bromobenzonitrile(cas: 2042-37-7Related Products of 2042-37-7)
2-Bromobenzonitrile(cas: 2042-37-7) is a precursor to the quinazolinones, a class of drugs used to treat autoimmune diseases and coronary heart disease. This substrate molecule undergoes a palladium-catalyzed coupling reaction to form an aromatic ring. The light emission from this reaction can be seen in the reaction solution.Related Products of 2042-37-7
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts