In 2007,Paillet-Loilier, Magalie; Fabis, Frederic; Lepailleur, Alban; Bureau, Ronan; Butt-Gueulle, Sabrina; Dauphin, Francois; Lesnard, Aurelien; Delarue, Catherine; Vaudry, Hubert; Rault, Sylvain published 《Novel aminoethylbiphenyls as 5-HT7 receptor ligands》.Bioorganic & Medicinal Chemistry Letters published the findings.Product Details of 31938-07-5 The information in the text is summarized as follows:
The synthesis of a series of aminoethylbiphenyls, e.g., I, as novel 5-HT7 receptor ligands is described. The novel derivatives exhibit high affinity for the 5-HT7 receptor with selectivity toward 5-HT1A receptor. In the experiment, the researchers used many compounds, for example, 2-(3-Bromophenyl)acetonitrile(cas: 31938-07-5Product Details of 31938-07-5)
According to other reports, 2-(3-Bromophenyl)acetonitrile(cas: 31938-07-5) is used in the preparation of diarylpyrimidines (DAPYs) as HIV-1 non-nucleoside reverse transcriptase inhibitors.Product Details of 31938-07-5
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts