Mo, Xueling; Chen, Bin; Zhang, Guozhu published the artcile< Copper-Catalyzed Enantioselective Sonogashira Type Coupling of Alkynes with α-Bromoamides>, Category: nitriles-buliding-blocks, the main research area is copper catalyst enantioselective Sonogashira coupling alkyne alpha bromoamide; Sonogashira reaction; copper catalysis; enantioselectivety; terminal alkynes; α-bromoamide.
An asym. copper-catalyzed Sonogashira type coupling between alkynes and α-bromoamides was developed. This method represents a facile approach to synthetically useful β, γ-alkynyl amides from two readily available starting materials in a highly enantioselective manner. A Bisoxazoline diphenylaniline (BOPA) serves as the effective chiral ligand. Preliminary mechanistic studies support the formation of alkyl radical species.
Angewandte Chemie, International Edition published new progress about Alkynes Role: RCT (Reactant), RACT (Reactant or Reagent). 94087-40-8 belongs to class nitriles-buliding-blocks, and the molecular formula is C7H3ClFN, Category: nitriles-buliding-blocks.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts