Kasina, Krishna Chaitanya; Rapeti, Siva Kumar; Sadhukhan, Arghya; Ranga, Mahesh; Pal, Arani; Birudaraju, Saritha; Tirukkovalluri, Siva rao published their research in Chemistry of Heterocyclic Compounds (New York, NY, United States) in 2021. The article was titled 《Silver-assisted palladium-catalyzed one-pot synthesis of 3-(hetero)arylmethyl derivatives of imidazo[1,2-a]pyridines》.HPLC of Formula: 2042-37-7 The article contains the following contents:
3-(Hetero)arylmethyl derivatives of imidazo[1,2-a]pyridine were synthesized by a novel one-pot method consisting of the Sonogashira coupling of tert-Bu prop-2-yn-1-yl(pyridin-2-yl)carbamate with different substituted (hetero)aryl bromides and cyclization of the in-situ obtained intermediate substituted (hetero)aryl acetylene derivatives In the experimental materials used by the author, we found 2-Bromobenzonitrile(cas: 2042-37-7HPLC of Formula: 2042-37-7)
2-Bromobenzonitrile(cas: 2042-37-7) is a precursor to the quinazolinones, a class of drugs used to treat autoimmune diseases and coronary heart disease. This substrate molecule undergoes a palladium-catalyzed coupling reaction to form an aromatic ring. The light emission from this reaction can be seen in the reaction solution.HPLC of Formula: 2042-37-7
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts