In 2015,Kahveci, Bahittin; Yilmaz, Fatih; Mentese, Emre; Ulker, Serdar published 《Microwave-assisted synthesis of some new coumarin derivatives including 1,2,4-triazol-3-one and investigation of their biological activities》.Chemistry of Heterocyclic Compounds (New York, NY, United States) published the findings.Recommanded Product: 31938-07-5 The information in the text is summarized as follows:
By using the microwave technol., a new protocol has been developed for the synthesis of new coumarin derivatives I [ R1 = H, Br; R = Me, 4-Cl-C6H4-CH2-, 4-Br-C6H4-CH2-, etc.] including 1,2,4-triazol-3-one skeleton. This protocol proves to be efficient and environmentally friendly in terms of easy work-up and good yields. All newly synthesized compounds were screened for their antimicrobial activity and lipase inhibition. Most of the compounds were found to be effective on Escherichia coli. Compounds I [R1 = Br, R = 2-Br-C6H4-CH2-; R1 = Br, R2 = 3,4-dichlorobenzyl] had a good effect on lipase inhibition. In the experimental materials used by the author, we found 2-(3-Bromophenyl)acetonitrile(cas: 31938-07-5Recommanded Product: 31938-07-5)
2-(3-Bromophenyl)acetonitrile(cas: 31938-07-5) has been used in the synthesis of 2-(1-cyano-1-(3-bromophenyl))methylidene-3-phenylthiazolidine-4,5-dione or a series of aminoethylbiphenyls, novel 5-HT7 receptor ligands.Recommanded Product: 31938-07-5
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts