Feng, Jian-Bo; Wu, Xiao-Feng published the artcile< Synthesis of quinazolinimines and quinazolinamines from 2-fluorobenzonitriles under catalyst-free conditions>, Recommanded Product: 3-Chloro-2-fluorobenzonitrile, the main research area is pyridoquinazolinimine preparation; aminopyridine fluorobenzonitrile cyclization nucleophilic aromatic substitution; quinazolinamine preparation; amidine fluorobenzonitrile cyclization nucleophilic aromatic substitution.
A convenient procedure for the synthesis of pyrido[1,2-a]quinazolinimines e.g., I and quinazolinamines e.g., II was developed via cyclization of 2-fluorobenzonitriles with 2-aminopyridines or amidines resp. through SNAr reactions using potassium tert-butoxide as the promoter. Using this methodol., the desired pyrido[1,2-a]quinazolinimines and quinazolinamines were obtained in moderate to good yields under catalyst-free conditions.
Organic & Biomolecular Chemistry published new progress about Amidines Role: RCT (Reactant), RACT (Reactant or Reagent). 94087-40-8 belongs to class nitriles-buliding-blocks, and the molecular formula is C7H3ClFN, Recommanded Product: 3-Chloro-2-fluorobenzonitrile.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts