In 2019,Chemical Communications (Cambridge, United Kingdom) included an article by Echemendia, Radell; da Silva, Gustavo P.; Kawamura, Meire Y.; de la Torre, Alexander F.; Correa, Arlene G.; Ferreira, Marco A. B.; Rivera, Daniel G.; Paixao, Marcio W.. COA of Formula: C9H7NO. The article was titled 《A stereoselective sequential organocascade and multicomponent approach for the preparation of tetrahydropyridines and chimeric derivatives》. The information in the text is summarized as follows:
A stereoselective multicomponent approach leading to a novel class of pentasubstituted tetrahydropyridines was described. Variation of the components enabled the incorporation of peptide, sugar and steroid moieties to access chimeric derivatives DFT calculations provided insights about the unprecedented high diastereoselectivity of the MCR.3-Oxo-3-phenylpropanenitrile(cas: 614-16-4COA of Formula: C9H7NO) was used in this study.
3-Oxo-3-phenylpropanenitrile(cas: 614-16-4) has been used to produce 2-benzoyl-3-furan-2-yl-acrylonitrile. It is an active methylene compound, useful in heterocyclic synthesis, e.g. polyfunctional pyridines and pyrimidines.COA of Formula: C9H7NO
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts