《Synthesis of difluoromethyl and deuterium-labeled difluoromethyl thioethers from aliphatic electrophiles》 was published in Chemical Communications (Cambridge, United Kingdom) in 2020. These research results belong to Ding, Tianqi; Jiang, Lvqi; Yi, Wenbin. SDS of cas: 17201-43-3 The article mentions the following:
A one-pot difluoromethylthiolation of alkyl electrophiles with thiourea and di-Et bromodifluoromethylphosphonate is described. The transition-metal-free approach, readily available reagents, and mild conditions provide a practical way for the synthesis of difluoromethyl thioethers. By changing the “”H”” source to the most commonly used “”D”” sources CD3OD and D2O, this strategy enables efficient synthesis of SCF2D-substituted mols. in good yields with high levels of D incorporation. In addition to this study using 4-Cyanobenzyl bromide, there are many other studies that have used 4-Cyanobenzyl bromide(cas: 17201-43-3SDS of cas: 17201-43-3) was used in this study.
4-Cyanobenzyl bromide(cas: 17201-43-3) is a white solid. Its melting point is 113-117°C, and flash point is 125.1°C. It is insoluble in water at 20°C. It is stable under normal temperatures and pressures. It should be stored at 0-5°C.SDS of cas: 17201-43-3
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts