Whyte, Andrew; Burton, Katherine I.; Zhang, Jingli; Lautens, Mark published the artcile< Enantioselective Intramolecular Copper-Catalyzed Borylacylation>, Quality Control of 94087-40-8, the main research area is enantioselective intramol copper catalyst borylacylation; mol structure crystal boronic ester preparation chiral; asymmetric catalysis; boron; copper; cyclizations; heterocycles.
An enantioselective copper-catalyzed intramol. borylacylation is reported. The reaction proceeds through an initial enantioselective borylcupration of the styrene, followed by a nucleophilic attack on the tethered carbamoyl chloride. The products, chiral borylated 3,3-disubstituted oxindoles, were generated in excellent yields and enantioselectivities. The versatile carbon-boron bond provides a platform for a wide array of diversification.
Angewandte Chemie, International Edition published new progress about Acylation, stereoselective. 94087-40-8 belongs to class nitriles-buliding-blocks, and the molecular formula is C7H3ClFN, Quality Control of 94087-40-8.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts