Murakami, Teiichi; Otsuka, Masami; Kobayashi, Susumu; Ohno, Masaji published the artcile< Synthesis of 2-formyladenosine using diethoxyacetonitrile as a synthon>, Name: 2,2-Diethoxyacetonitrile, the main research area is formyladenosine; adenosine formyl; formyladenine; adenine formyl; aminoribofuranosylimidazolecarbonitrile cyclization diethoxyacetonitrile; nucleoside formyladenosine.
Imidazole I was heated with (EtO)2CHCN in BuOH-pyridine at 120° for 10 min in the presence of BuONa to give 90% nucleoside II [R = CH(COEt)2] which on hydrolysis with H2O-AcOH gave 96% II (R = CHO). II (R = CHO) was further converted into II (R = CH:NOH) and II (R = cyano). 2-Formyladenine was analogously prepared
Heterocycles published new progress about Cyclization. 6136-93-2 belongs to class nitriles-buliding-blocks, and the molecular formula is C6H11NO2, Name: 2,2-Diethoxyacetonitrile.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts