Jia, Qianfa; Yin, Guoliang; Lan, Yunfei; Lin, Yinhe; Ren, Qiao published the artcile< Base-mediated Benzannulation Reactions for the Synthesis of Densely Functionalized Aryl α-Keto Esters>, Computed Properties of 21667-62-9 , the main research area is phenyl keto ester preparation; cyano phenyl methanone ynedione regioselective cycloaddition.
A novel and straightforward strategy for the construction of versatile densely functionalized aryl α-keto esters were disclosed through a one-pot and efficient [4+2] benzannulation reaction of α-cyano-β-methylenones and ynediones, which were synthesized easily from the corresponding starting materials. This protocol featured high yield, mild metal-free reaction condition, high atom economy, high functional-group tolerance, easy handing and gram-scale synthesis.
Asian Journal of Organic Chemistry published new progress about [4+2] Cycloaddition reaction (regioselective). 21667-62-9 belongs to class nitriles-buliding-blocks, and the molecular formula is C9H6ClNO, Computed Properties of 21667-62-9 .
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts