Bagley, Mark C.; Glover, Christian published the artcile< Synthesis of methyl sulfomycinate, sulfomycinic amide and sulfomycinine, degradation products of the sulfomycin thiopeptide antibiotics>, Recommanded Product: 2,2-Diethoxyacetonitrile, the main research area is sulfomycin thiopeptide antibiotic methanolysis product synthesis methyl sulfomycinate; sulfomycinic amide sulfomycinine synthesis sulfomycin thiopeptide antibiotic degradation product; methyl sulfomycinate ammonolysis hydrolysis sulfomycinine; thiazole oxazole building block peptide coupling.
The convergent synthesis of Me sulfomycinate and sulfomycinic amide, two acidic methanolysis products of the sulfomycin thiopeptide antibiotics, is achieved starting from diethoxyacetonitrile. Further confirmation of structure is obtained by heating Me sulfomycinate at 110 °C in hydrochloric acid to give (±)-sulfomycinine hydrochloride, the acid hydrolyzate of sulfomycin I.
Tetrahedron published new progress about Ammonolysis. 6136-93-2 belongs to class nitriles-buliding-blocks, and the molecular formula is C6H11NO2, Recommanded Product: 2,2-Diethoxyacetonitrile.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts