Ali, Abdelselam; Bliese, Marianne; Rasmussen, Jo-Anne M.; Sargent, Roger M.; Saubern, Simon; Sawutz, David G.; Wilkie, John S.; Winkler, David A.; Winzenberg, Kevin N.; Woodgate, Ruth C. J. published the artcile< Discovery of (Z)-2-phenyl-3-(1H-pyrrol-2-yl)acrylonitrile derivatives active against Haemonchus contortus and Ctenocephalides felis (cat flea)>, Synthetic Route of 658-99-1, the main research area is phenylpyrrolyl acrylonitrile derivative preparation antiparasitic activity.
A series of 2-phenyl-3-(1H-pyrrol-2-yl)acrylonitrile derivatives, e.g., I, were synthesized and evaluated for in vitro activity against the endoparasite Haemonchus contortus and the ectoparasite Ctenocephalides felis. Some compounds had significant in vitro activity against these parasites.
Bioorganic & Medicinal Chemistry Letters published new progress about Parasitic infection. 658-99-1 belongs to class nitriles-buliding-blocks, and the molecular formula is C8H5F2N, Synthetic Route of 658-99-1.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts