Industrially, the main methods for producing nitriles are ammoxidation and hydrocyanation. 31643-49-9, formula is C8H3N3O2, Name is 4-Nitrophthalonitrile. Both routes are green in the sense that they do not generate stoichiometric amounts of salts. Safety of 4-Nitrophthalonitrile.
Gonzalez, Andreia C. S.;Felgueiras, Alexandre P.;Aroso, Rafael T.;Carrilho, Rui M. B.;Pereira, Mariette M. research published 《 Al(III) phthalocyanine catalysts for CO2 addition to epoxides: Fine-tunable selectivity for cyclic carbonates versus polycarbonates》, the research content is summarized as follows. A sustainable synthetic methodol. to prepare bifunctional cationic imidazolyl and neutral tert-butylphenoxy Al(III)-phthalocyanine complexes is described, using ultrasound irradiation to synthesize the phthalonitrile precursors, followed by microwave-assisted cyclotetramerization. The metallophthalocyanine catalysts were applied in the coupling reaction of CO2 with epoxides, where the structure of the phthalocyanine was shown to determine the reaction selectivity towards the formation of cyclic carbonates vs. polycarbonates. The cationic imidazolyl phthalocyanines operate as efficient bifunctional catalysts to promote the CO2 cycloaddition to terminal epoxides (styrene oxide, epichlorohydrin, propylene oxide and allyl glycidyl ether), leading to TONs up to 1414 and 100% selectivity for cyclic carbonates, without the need of using any co-catalyst. On the other hand, the neutral 4-tert-butylphenoxy Al(III) phthalocyanine catalyzed the copolymerization reaction between CO2 and cyclohexene oxide, in the presence of PPNCl as co-catalyst, with TON = 814, providing the first example of a metallophthalocyanine catalyst with full selectivity for formation of polycarbonates.
Safety of 4-Nitrophthalonitrile, 4-Nitrophthalonitrile, also known as 4-Nitrophthalonitrile, is a useful research compound. Its molecular formula is C8H3N3O2 and its molecular weight is 173.13 g/mol. The purity is usually > 95%.
4-Nitrophthalonitrile is a chemical substance that can be synthesized by the reaction of sodium carbonate with 3,4,5-trimethoxybenzyl alcohol. It can also be prepared using nitro phenol and sodium hydroxide. 4-Nitrophthalonitrile has been shown to have high photochemical activity in the presence of light. The frequency shift of its infrared spectrum is indicative of a nucleophilic addition reaction mechanism. 4-Nitrophthalonitrile has been used as an intermediate for producing other chemicals, such as herbicides and pharmaceuticals., 31643-49-9.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts