Nitriles used to be known as cyanides; the smallest organic nitrile is ethanenitrile, CH3CN, (old name: methyl cyanide or acetonitrile – and sometimes now called ethanonitrile). 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Nitriles are found in many useful compounds, including methyl cyanoacrylate, used in super glue, and nitrile rubber, a nitrile-containing polymer used in latex-free laboratory and medical gloves. Name: 4-Ethynylbenzonitrile.
Fan, Zhe;Ni, Shao-Fei;Pang, Jin-Yu;Guo, Li-Ting;Yang, Hao;Li, Ke;Ma, Cheng;Liu, Ji-Kai;Wu, Bin;Yang, Jin-Ming research published 《 Cu(I)-Catalyzed Cross-Coupling Rearrangements of Terminal Alkynes with Tropylium Tetrafluoroborate: Facile Access to Barbaralyl-Substituted Allenyl Acid Esters and 7-Alkynyl Cycloheptatrienes》, the research content is summarized as follows. Herein, a novel strategy for the formation of copper carbene via the cycloisomerization of the π-alkyne-Cu(I) complex from terminal alkynes RCCH [R = MeOC(O), BnOC(O), Ph, 1-naphthyl, 3-thienyl, etc.] and tropylium tetrafluoroborate was reported. Mechanistic studies and DFT calculations indicate that the reaction undergoes the intramol. cycloisomerization process from the π-alkyne-Cu(I) complex to afford the copper carbene intermediate, followed by migratory insertion with the second terminal alkyne to afford the barbaralyl-substituted allenyl acid esters I. In addition, a mild and highly efficient Cu(I)-catalyzed cross-coupling protocol to synthesize 7-alkynyl cycloheptatrienes II that has a broad functional group tolerance is developed and it is applicable to the late-stage functionalization of natural products.
3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.
4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., Name: 4-Ethynylbenzonitrile
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts