Nitrile groups in organic compounds can undergo a variety of reactions depending on the reactants or conditions. 105-34-0, formula is C4H5NO2, Name is Methyl 2-cyanoacetate. A nitrile group can be hydrolyzed, reduced, or ejected from a molecule as a cyanide ion. Related Products of 105-34-0.
Dutta, Arup;Goswami, Munmee;Rabha, Jintu;Das, Sukanya;Jha, Dhruva K.;Nongkhlaw, Rishanlang research published 《 Fe3O4@RB@LDH: Efficient and Recyclable Photocatalyst Visible-Light Mediated Synthesis of Pyran and Pyrrolidinone Derivatives and Their Anti-Microbial Activities》, the research content is summarized as follows. Selective and high yielding synthesis of pyrans, e.g., I and pyrrolidinone derivatives II [R = H, Cl, Me, OMe; R1 = H, 3-Cl, 4-OH, etc.; R2 = Me, Et] through a magnetic layered double hydroxide (LDH) visible light photocatalyst (VLPC)-promoted reaction is reported. The catalyst was prepared and characterized by various anal. techniques. Since it is magnetic the prepared catalyst could be easily separated from the reaction mixture by using an external magnet. The advantages of this synthetic protocol are good to excellent yields, short reaction times, easy catalyst recovery and recyclability. Also, in vitro antibacterial screening of pyrrolidinone derivative II was studied against gram-pos. Bacillus cereus (B. cereus), gram-neg. bacteria Escherichia coli (E. coli) and S. aureus. Compound II [R = H, R1 = 3-Cl, R2 = Me] exhibited the maximum activity against all the bacteria tested in the experiment
Related Products of 105-34-0, Methyl cyanoacetate is an alkyl cyanoacetate ester.
Methyl cyanoacetate is the intermediate product in pharmaceutical organic synthesis as well as in the synthesis of some biologically active compounds used in agriculture. It undergoes calcite or fluorite catalyzed Knövenagel condensation with aromatic aldehydes, giving the corresponding arylidenemalononitriles and (E)-α -cyanocinnamic esters.
Methyl Cyanoacetate is often used as a nucleophile in the electrochemical oxidation of catechols. Methyl Cyanoacetate is also a reagent in the synthesis of Methyl 2-Amino-4-trifluoromethylthiophene-3-carboxylate (M287290); a compound used in the synthesis of DPP-IV inhibitors for treating type 2 diabetes., 105-34-0.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts