Industrially, the main methods for producing nitriles are ammoxidation and hydrocyanation. 105-34-0, formula is C4H5NO2, Name is Methyl 2-cyanoacetate. Both routes are green in the sense that they do not generate stoichiometric amounts of salts. HPLC of Formula: 105-34-0.
Divar, Masoumeh;Zomorodian, Kamiar;Sabet, Razieh;Moeini, Maryam;Khabnadideh, Soghra research published 《 An Efficient Method for Synthesis of Some Novel Spirooxindole-4H-Pyran Derivatives》, the research content is summarized as follows. In this study, an easy and efficient access to spirooxindoles I (R = Et, cyclopentyl, (3-bromophenyl)methyl, etc.; R1 = CN, C(O)OCH3, C(O)OCH2CH3) by multicomponent reaction of N-alkylated isatin derivatives II, an activated methylene R1CH2CN and 4-hydroxycoumarin to get such compounds powerfully and suitably was proposed. The reaction conditions were also optimized in the point of different kinds of catalysts, temperature, and solvents.
105-34-0, Methyl cyanoacetate is an alkyl cyanoacetate ester.
Methyl cyanoacetate is the intermediate product in pharmaceutical organic synthesis as well as in the synthesis of some biologically active compounds used in agriculture. It undergoes calcite or fluorite catalyzed Knövenagel condensation with aromatic aldehydes, giving the corresponding arylidenemalononitriles and (E)-α -cyanocinnamic esters.
Methyl Cyanoacetate is often used as a nucleophile in the electrochemical oxidation of catechols. Methyl Cyanoacetate is also a reagent in the synthesis of Methyl 2-Amino-4-trifluoromethylthiophene-3-carboxylate (M287290); a compound used in the synthesis of DPP-IV inhibitors for treating type 2 diabetes., HPLC of Formula: 105-34-0
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts