Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 17524-05-9, is researched, Molecular C10H14MoO6, about An insight into the potent antioxidant activity of a dithiocarbohydrazone appended cis-dioxidomolybdenum (VI) complexes, the main research direction is crystal structure oxomolybdenum dithiocarbohydrazone methanol DMSO aqua complex; oxomolybdenum dithiocarbohydrazone preparation antioxidant mol docking enzyme 3MNG.Formula: C10H14MoO6.
In search of antioxidants with enriched potency, the present study focus on the design and synthesis of a dithiocarbohydrazone, H3TCL derived from thiocarbohydrazide and 3-ethoxysalicylaldehyde and its coordination complexes with Mo, viz, [MoO2(HTCL)D] (D = MeOH 1, DMSO 2) and [MoO2(HTCL)D]·DMF (D = H2O 3). The synthesized compounds were characterized by elemental anal., spectroscopic techniques (FTIR, UV-visible and 1H-NMR), conductivity measurements and cyclic voltammetry. Also the solid state structures of all the three complexes were established by single crystal x-ray diffraction anal. as mononuclear neutral species in which the Mo center assumes a distorted octahedral geometry. The dithiocarbohydrazone binds to the Mo center through its phenolate O, O(1), azomethine N, N(1) and thioenolate S, S(1) in a dianionic tridentate mode. The assessment of intermol. contacts in the crystal arrangement was quantified using Hirshfeld surface anal. Further the antioxidant potential of the dithiocarbohydrazone, H3TCL and its Mo complexes 1-3 were evaluated using 1,1-diphenyl-2-picrylhydrazyl(DPPH), 2,2′-azinobis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS) and total antioxidant assays. The antioxidant activities were then compared with standard antioxidant, L-ascorbic acid. The antioxidant potential of the synthesized compounds were then validated by mol. docking studies. Mol. modeling study was achieved to evaluate the recognition of target compound at the binding pocket of the human antioxidant enzyme, 3MNG. The docking results showed that the complexes selectively bond to the vital amino acids present in the binding pocket of the target enzyme, 3MNG.
Different reactions of this compound(Bis(acetylacetonato)dioxomolybdenum(VI))Formula: C10H14MoO6 require different conditions, so the reaction conditions are very important.
Reference:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts