In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Recyclable Raman chip for detection of trace Mercury ions, published in 2020-06-15, which mentions a compound: 4556-23-4, mainly applied to pyridinethiol maercury ion Raman mol orientation recyclable chip, Computed Properties of C5H5NS.
Due to enrichment effect of Mercury ions (Hg2+), even if the concentration of Hg2+ is very low, it will do harm to human health. Precise detection of trace Hg2+ is important for environment protection and human health monitoring. In this work, gold nanoparticles (AuNPs) are immobilized on the surface of ITO with aid of inositol-hexaphosphate as linker agent and then 4-pyridinethiol (4-MPy) is decorated to form a 4-MPy/AuNPs/ITO chip. 4-MPy in the chip acts two roles involving the capture agent for Hg2+ and Raman signal reporter. With the adding of Hg2+, the linear increase of SERS response of 4-MPy is in the range from 1.0 ppt to 100 ppb (R2 = 0.9896) and the limit of detection could be down to 1 precipitate The mechanism of the Raman chip was also explored by mol. simulation. It is found that the interaction between Hg2+ and the nitrogen atoms changes the electron distribution of pyridine ring and induces reorientation of the 4-MPy mols. tending to more perpendicular adsorption fashion with respect to AuNPs surface, which leads to enhancement of the intensity of the pyridine breathing vibration peak at 1093 cm-1. The as-prepared SERS sensor chip features excellent stability and reproducibility as well as could be reused. The rapid 4-MPy/AuNPs/ITO-chip-based Raman protocol with capability against interference is competent for monitoring trace Hg2+ in river water samples.
Different reactions of this compound(Pyridine-4-thiol)Computed Properties of C5H5NS require different conditions, so the reaction conditions are very important.
Reference:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts