In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called A new nanocomposite catalyst based on clay-supported heteropolyacid for the green synthesis of 2,4,5-trisubstituted imidazoles, published in 2020-08-31, which mentions a compound: 484-47-9, mainly applied to imidazole preparation green chem; benzil benzaldehyde heterocyclization nanocatalyst, Application of 484-47-9.
Intercalation of cetyltrimethylammonium (CTA+) cations within the nanolayers of montmorillonite (MMT) clay followed by reaction with Keggin-type phosphomolybdic acid (PMo) resulted in the synthesis of (CTA)3PMo-MMT nanocomposite catalyst. The prepared nanocomposite catalyst was characterized using different physicochem. methods such as Fourier-transform IR and inductively coupled plasma-optical emission spectroscopies, X-ray diffraction, and nitrogen adsorption-desorption (Brunauer-Emmett-Teller method) analyses. Characterization techniques demonstrated the intercalation of (CTA)3PMo species into the nanolayers of MMT. The resulting (CTA)3PMo-MMT nanocomposite catalyst efficiently catalyzed the synthesis of 2,4,5-trisubstituted imidazoles I (R = 4-chlorophenyl, 2-bromophenyl, 1-naphthyl, etc.) under solvent-free conditions. The efficiency is due to the fact that the presence of CTA+ species makes the nanocomposite catalyst hydrophobic and facilitates the accessibility of hydrophobic reactants to active sites in the course of the reaction. High activity and selectivity were achieved in the presence of the prepared nanocomposite catalyst. The nanocomposite catalyst was readily isolated from the reaction mixture using simple filtration, washed with ethanol, and recycled five times without a major loss of activity.
The article 《A new nanocomposite catalyst based on clay-supported heteropolyacid for the green synthesis of 2,4,5-trisubstituted imidazoles》 also mentions many details about this compound(484-47-9)Application of 484-47-9, you can pay attention to it, because details determine success or failure
Reference:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts