Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 484-47-9, is researched, SMILESS is C1(C2=CC=CC=C2)=NC(C3=CC=CC=C3)=C(C4=CC=CC=C4)N1, Molecular C21H16N2Journal, RSC Advances called Novel synthesis of divergent aryl imidazoles from ketones involving copper-catalyzed α-amination and oxidative C-C bond cleavage, Author is Huang, Jiangkun; Luo, Lan; Xing, Naiguo; Gu, Linghui; Li, Chen; Han, Qiao; Zheng, Shilong; He, Ling, the main research direction is aryl imidazole preparation; ketone amination oxidative bond cleavage copper catalyst; aldehyde ketone amination oxidative bond cleavage copper catalyst.Formula: C21H16N2.
A one-pot synthesis, initiated by a copper salt with inorganic (NH4)2CO3 as the nitrogen source, forms divergent aryl imidazole derivatives I [R = H, Et, thiophen-2-yl, naphthalen-1-yl, 2H-1,3-benzodioxol-5-yl, etc.; R1 = Me, Et, n-Pr, Ph; Ar = 4-bromophenyl, thiophen-2-yl, 2,3-dihydro-1,4-benzodioxin-6-yl, etc.] and II [Ar1 = 1H-indol-3-yl, 2-phenyl-1H-indol-3-yl, 5-bromo-1H-indol-3-yl, etc.; Ar2 = Ph, 4-methylphenyl; R2 = Me, 4-methylphenyl; R3 = Me, Et] from ketones ArC(O)CH2R/Ar1C(O)CH2Ar2/R2C(O)(R3) via α-amination and oxidative C-C bond cleavage reactions. The approach provides a simple and rapid synthesis of imidazole derivatives I and II and has certain versatility.
As far as I know, this compound(484-47-9)Formula: C21H16N2 can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.
Reference:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts