Pei, Chunzhe; Zong, Jiarui; Han, Shanglin; Li, Bin; Wang, Baiquan published an article about the compound: 7-Methoxy-1H-indole-3-carboxylic acid( cas:128717-77-1,SMILESS:O=C(C1=CNC2=C1C=CC=C2OC)O ).Synthetic Route of C10H9NO3. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:128717-77-1) through the article.
The transition-metal-catalyzed direct carboxylation of an unactivated C-H bond is rarely reported, and no example of catalysis using abundant and cheap nickel has been reported. In this work, the first Ni-catalyzed direct carboxylation of an unactivated C-H bond under an atm. pressure of CO2 is reported. This method affords moderate to high carboxylation yields of various Me carboxylates under mild conditions. Preliminary mechanistic studies reveal that a Ni(0)-Ni(II)-Ni(I) catalytic cycle may be involved in this reaction.
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Reference:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts