Safety of 2,4,5-Triphenylimidazole. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: 2,4,5-Triphenylimidazole, is researched, Molecular C21H16N2, CAS is 484-47-9, about Homoselective synthesis of 5-substituted 1H-tetrazoles and one-pot synthesis of 2,4,5-trisubstituted imidazole compounds using BNPs@SiO2-TPPTSA as a stable and new reusable nanocatalyst. Author is Khodamorady, Minoo; Ghobadi, Nazanin; Bahrami, Kiumars.
Considering the importance of tetrazole and imidazole derivatives in pharmacy, industry, and explosives, BNPs@SiO2-TPPTSA was easily prepared and used as an effective, stable, and renewable nanocatalyst for the homoselective synthesis of different 5-substituted 1H-tetrazoles and atom economic synthesis of 2,4,5-trisubstituted-1H-imidazoles in solventless conditions. BNPs@SiO2-TPPTSA was characterized by transmission electron microscopy (TEM), SEM (SEM), X-ray diffraction (XRD), energy dispersive X-ray anal. (EDX), thermal gravimetric-DTA (TGA-DTA), mapping, pH anal., and Fourier transform IR (FT-IR) techniques. Furthermore, the catalyst recycled for at least sequential five loads without a remarkable drop-in catalytic activity.
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Reference:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts