In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called A concise synthesis of (2S,3S)-BocAHPBA and (R)-BocDMTA, chiral building blocks for peptide-mimetic HIV protease inhibitors, published in 2002-06-21, which mentions a compound: 117918-23-7, Name is (R)-3-(tert-Butoxycarbonyl)-5,5-dimethylthiazolidine-4-carboxylic acid, Molecular C11H19NO4S, SDS of cas: 117918-23-7.
Scalable syntheses of (2S,3S)-3-N-tert-butoxycarbonylamino-2-hydroxy-4-phenylbutanoic acid (BocAHPBA) and (R)-3-tert-butoxycarbonyl-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid (BocDMTA) have been developed. Both BocAHPBA and BocDMTA can serve as chiral building blocks in assembling JE-2147 (KNI-764), a potent HIV protease inhibitor. The synthesis of (2S,3S)-BocAHPBA is achieved in 41% overall yield from (S)-2-N,N-dibenzylamino-3-phenylpropanal in five steps where Tamao’s reagent [Me2(i-PrO)SiCH2MgCl] is employed for a one-carbon homologation, and Zhao’s oxidation protocol (TEMPO, NaClO2, NaClO) is applied to convert a 1,2-glycol moiety into an α-hydroxy acid motif. (R)-BocDMTA is synthesized with 99.4% ee in 24% yield via enantioselective hydrolysis of Me (±)-5,5-dimethyl-1,3-thiazolidine-4-carboxylate by a Klebsiella oxytoca hydrolase; the unreacted (S)-ester I can be recovered and racemized with NaOMe to afford (±)-I in 46% yield for another round of the enzymic processing.
Compound(117918-23-7)SDS of cas: 117918-23-7 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound((R)-3-(tert-Butoxycarbonyl)-5,5-dimethylthiazolidine-4-carboxylic acid), if you are interested, you can check out my other related articles.
Reference:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts