I found the field of Biochemistry & Molecular Biology; Chemistry very interesting. Saw the article Polysiloxane assisted fabrication of chiral crystal sponge coated capillary column for chiral gas chromatographic separation published in 2019. Category: nitriles-buliding-blocks, Reprint Addresses Yang, CX (corresponding author), Nankai Univ, Tianjin Key Lab Mol Recognit & Biosensing, Res Ctr Analyt Sci, Coll Chem, Tianjin 300071, Peoples R China.. The CAS is 95-11-4. Through research, I have a further understanding and discovery of 5-Norbornene-2-carbonitrile
Chiral crystalline sponges (CCSs) are a recent class of chiral porous metal complexes potential in chiral recognition. Here we report the fabrication of polysiloxane OV-1701 incorporated CCS-3S (PSO/CCS-3S) coated capillary column as a novel stationary phase for gas chromatographic separation of diverse race-mates. CCS-3S with the chiral ligand of (S)-mandelic was selected as the model CCS. With the aid of polysiloxane OV-1701, PSO/CCS-3S coated capillary column gave improved resolution, broader enantiomers separation scope and much larger McReynolds constants than CCS-3S coated capillary column. Many racemates that cannot be separated on CCS-3S coated capillary column were well resolved on PSO/CCS-3S coated capillary column. The PSO/CCS-3S coated capillary column also gave wide linear range, low limit of detection, good repeatability and reproducibility, and fine inertness and anti-column bleeding properties for the separation of enantiomers. In addition, the PSO/CCS-3S coated capillary column presented better resolution for the studied racemates than commercial beta-cyclodextrin based Cyclosil B (30 m long x0.32 mm i.d. x 0.25 mu m film thickness), beta-DEX 225 (30 m long x0.25 mm i.d. x 0.25 mu m film thickness) and amino acid based Chirasil L-Val (25 m long x0.25 mm i.d. x 0.12 mu m film thickness) capillary columns. These results indicate the great potential of PSO/CCS-3S coated capillary column in separation of enantiomers. (C) 2019 Elsevier B.V. All rights reserved.
Category: nitriles-buliding-blocks. Welcome to talk about 95-11-4, If you have any questions, you can contact Wang, ZM; Yang, CX; Yan, XP or send Email.
Reference:
Patent; Mitsui Chemicals, Inc.; KUMA, Shigetoshi; SAKATA, Michiharu; TOKUNAGA, Kouichi; SHIMAKAWA, Chitoshi; KAKINUMA, Naoyuki; FURUYA, Masayuki; TANAKA, Mamoru; EP2708527; (2014); A1;,
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