Category: nitriles-buliding-blocks. I found the field of Biochemistry & Molecular Biology; Chemistry very interesting. Saw the article Polysiloxane assisted fabrication of chiral crystal sponge coated capillary column for chiral gas chromatographic separation published in 2019, Reprint Addresses Yang, CX (corresponding author), Nankai Univ, Tianjin Key Lab Mol Recognit & Biosensing, Res Ctr Analyt Sci, Coll Chem, Tianjin 300071, Peoples R China.. The CAS is 95-11-4. Through research, I have a further understanding and discovery of 5-Norbornene-2-carbonitrile.
Chiral crystalline sponges (CCSs) are a recent class of chiral porous metal complexes potential in chiral recognition. Here we report the fabrication of polysiloxane OV-1701 incorporated CCS-3S (PSO/CCS-3S) coated capillary column as a novel stationary phase for gas chromatographic separation of diverse race-mates. CCS-3S with the chiral ligand of (S)-mandelic was selected as the model CCS. With the aid of polysiloxane OV-1701, PSO/CCS-3S coated capillary column gave improved resolution, broader enantiomers separation scope and much larger McReynolds constants than CCS-3S coated capillary column. Many racemates that cannot be separated on CCS-3S coated capillary column were well resolved on PSO/CCS-3S coated capillary column. The PSO/CCS-3S coated capillary column also gave wide linear range, low limit of detection, good repeatability and reproducibility, and fine inertness and anti-column bleeding properties for the separation of enantiomers. In addition, the PSO/CCS-3S coated capillary column presented better resolution for the studied racemates than commercial beta-cyclodextrin based Cyclosil B (30 m long x0.32 mm i.d. x 0.25 mu m film thickness), beta-DEX 225 (30 m long x0.25 mm i.d. x 0.25 mu m film thickness) and amino acid based Chirasil L-Val (25 m long x0.25 mm i.d. x 0.12 mu m film thickness) capillary columns. These results indicate the great potential of PSO/CCS-3S coated capillary column in separation of enantiomers. (C) 2019 Elsevier B.V. All rights reserved.
About 5-Norbornene-2-carbonitrile, If you have any questions, you can contact Wang, ZM; Yang, CX; Yan, XP or concate me.. Category: nitriles-buliding-blocks
Reference:
Patent; Mitsui Chemicals, Inc.; KUMA, Shigetoshi; SAKATA, Michiharu; TOKUNAGA, Kouichi; SHIMAKAWA, Chitoshi; KAKINUMA, Naoyuki; FURUYA, Masayuki; TANAKA, Mamoru; EP2708527; (2014); A1;,
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